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Table 3 GO consistency and coverage comparison on IntAct dataset

From: ClusterM: a scalable algorithm for computational prediction of conserved protein complexes across multiple protein interaction networks

PPI networks

measure

MaWISh

AlignMCL

NB-M

CM1

CM10

CM100

SceIntAct+HsaIntAct

MNE

4.734

3.137

4.028

3.089

3.103

3.018

 

Coverage

1552

4181

478

6355

6216

3023

SceIntAct+DmeIntAct

MNE

3.679

2.705

4.208

2.307

2.310

2.446

 

Coverage

1548

1290

423

2403

2391

1209

SceIntAct+CelIntAct

MNE

3.378

2.918

3.679

2.647

2.635

2.697

 

Coverage

797

818

346

1578

1543

637

HsaIntAct+DmeIntAct

MNE

7.587

4.148

4.988

3.421

3.477

3.668

 

Coverage

4413

5898

219

7069

6730

1941

HsaIntAct+CelIntAct

MNE

6.463

4.490

4.639

3.449

3.448

3.367

 

Coverage

2263

3724

167

4077

3907

1202

DmeIntAct+CelIntAct

MNE

4.497

4.013

5.154

2.745

2.785

2.477

 

Coverage

545

1120

204

1891

1833

520

SceIntAct+HsaIntAct+DmeIntAct

MNE

  

4.317

3.154

3.165

3.315

 

Coverage

  

631

8640

8354

4233

SceIntAct+HsaIntAct+CelIntAct

MNE

  

3.848

3.294

3.307

3.352

 

Coverage

  

408

6160

5952

2675

SceIntAct+DmeIntAct+CelIntAct

MNE

  

4.479

2.657

2.659

2.574

 

Coverage

  

640

3321

3222

1282

HasIntAct+DmeIntAct+CelIntAct

MNE

  

5.321

3.196

3.246

3.109

 

Coverage

  

435

6213

5895

2168

SceINTACT+HsaINTACT+DmeINTACT+CelINTACT

MNE

  

4.344

3.139

3.153

3.252

 

Coverage

  

456

5907

5668

2246

  1. Abbreviations: CM1 = ClusterM(λ=1), CM10 = ClusterM(λ=10), CM100 = ClusterM(λ=100), NME = Mean Normalized Entropy, NB-M = NetworkBLAST-M
  2. Note: Bold values denote the best scores corresponding to specific criteria
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BMC Genomics

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