Table 1 Results of hotspots identified by NICER using the yeast dataset. Putative regulators identified by previous studies are denoted in boldface [14,15,16,17,18,19,20]

1^*

chrII:117298_A/G

PIN4, SAS3, MOH1, PTC3

2

chrII:466295_A/G

TKL2, ALG1, YBR109W-A, YBR116C

3

chrII:498623_C/T

CKS1, VMA2, MEO1, YBR126W-B, CCZ1

4

chrII:586961_C/T

UMP1, YPC1, EHT1, RPS6B, SMP1, FZO1

5

chrIV:266824_T/C

TMA17, QRI1, MSS2, QRI7, NSE4, TRM3

6

chrIV:476833_C/T

GCV1, DAS2

7^*

chrIV:637663_A/T

YDR098C-B, GIS1, MSH6

8^*

chrVI:96802_G/A

FRS2, LPD1, MDJ1, GNA1, GAT1, SMX2

9^*

chrVII:362516_A/T

RPL7A, MPC1, HNM1, AFT1, SCY1, DBP3, YGL081W, YGL082W, MPS2

10^*

chrVIII:114337_G/A

GPA1, ERG11, OSH7, QCR10, TDA3

11^*

chrVIII:173637_G/T

DAP2, YHR033W, SLT2, ERC1, PUT2, PIH1, BRL1, RRM3

12^*

chrVIII:463786_G/A

STB5, OYE2, YHR177W, YHR182W, GND1

13

chrIX:216335_C/T

SPO22, THS1, SER33, YIL077C, SEC28

14

chrX:489283_A/G

RAD26, CPR7, RAV1, RBH2

15

chrX:568363_G/A

MOG1, OPI3, HAM1, HOC1, NPA3, CDC11

16^*

chrXI:232567_T/C

AAT1, HAP4, KTI12, YKL107W, APN1, SEG2, RAD27

17^*

chrXII:514845_A/C

YLR179C, TFS1, VTA1, SAM1, TOS4, YLR177W, CBF5

18^*

chrXII:650260_C/T

HAP1, MCP2

19^*

chrXIII:46211_C/T

BUL2, COQ5, VAN1, YML108W, YML116W-A, DAT1, CTK3, TAF8, ZDS2

20

chrXIII:110807_T/C

CPR3, HMG1, YML079W, WAR1, YML082W, TDA9, DUS1

21

chrXIII:333449_G/A

RCH1, IMP2, MIH1, FAR8

22

chrXIII:409642_T/A

AVO2

23^*

chrXIV:467219_A/G

TOP2

24^*

chrXIV:571166_T/C

HHT2, SIW14, CRZ1

25^*

chrXV:159827_A/G

PHM7

26^*

chrXV:177015_A/G

ATG19, AVO1, ATP19, IRA2

27^*

chrXV:520870_G/A

RAS1, PIN2, RGS2, LEU9, CRC1, KTR1, INP53, YOR105W, AM3, YOR111W

28^*

chrXV:552069_C/T

CAT5, GCY1, LEO1, RTC5, PFY1

29

chrXV:610420_C/A

SPP2, RPB2, PNO1, ELG1, MDM32