Table 3 Top eight up-regulated midgut transcripts upon Leishmania infection per time point
From: Leishmania infection induces a limited differential gene expression in the sand fly midgut
Time Point | Class | Transcript name | Putative Encoded Protein | E-value | LFC |
|---|---|---|---|---|---|
1d | tr | lulogutSigP-46,620 | Permease of the major facilitator superfamily | 9.00E-85 | 6.036 |
2d | pe | lulogut42669 | Endosomal membrane EMP70–10 predicted membrane helices | 0 | 6.449 |
met/aa | lulogut42063 | Glutamate decarboxylase | 0 | 2.361 | |
prot | lulogut44776 | E3 ubiquitin-protein ligase listerin-like | 0 | 1.508 | |
4d | imm | lulogutSigP-25,698 | Major epididymal secretory protein HE1 - signalP detected | 3.00E-12 | 2.443 |
s/ | lulogutSigP-646 | Insect allergen related repeat - signalP detected | 5.00E-28 | 2.306 | |
s/ | lulogutSigP-16,736 | Insect allergen related repeat - signalP detected | 4.00E-30 | 2.223 | |
s/ | lulogutSigP-13,949 | Insect allergen related repeat - signalP detected | 2.00E-42 | 2.164 | |
s/ | lulogutSigP-32,546 | Secreted metalloprotease | 0 | 2.021 | |
met/carb | lulogut24944 | Alpha-L-fucosidase - signalP detected | 0 | 1.843 | |
s/ | lulogutSigP-13,652 | Insect allergen related repeat - signalP detected | 2.00E-32 | 1.779 | |
met/aa | lulogutSigP-33,280 | Puromycin-sensitive aminopeptidase - signalP detected | 0 | 1.761 | |
6d | s/ | lulogutSigP-54,492 | Insect allergen related repeat - signalP detected | 5.00E-42 | 2.445 |
s/ | lulogutSigP-53,922 | Secreted metalloprotease | 0 | 2.404 | |
s/ | lulogutSigP-32,546 | Secreted metalloprotease | 7.00E-29 | 2.312 | |
pm | lulogutSigP-35,736 | Trypsin-like serine protease - signalP detected | 0 | 2.177 | |
pm | lulogut24040 | Peptide methionine sulfoxide reductase | 2.00E-58 | 2.102 | |
pm | lulogutSigP-1870 | Trypsin-like serine protease - signalP detected | 5.00E-67 | 1.842 | |
detox | lulogut45589 | JAV13729.1 glutathione s-transferase | 0 | 1.836 | |
s/ | lulogutSigP-13,652 | Insect allergen related repeat - signalP detected | 2.00E-32 | 1.759 | |
8d | pm | lulogutSigP-35,736 | Trypsin-like serine protease - signalP detected | 2.00E-58 | 1.719 |
met/aa | lulogutSigP-39,956 | Puromycin-sensitive aminopeptidase - signalP detected | 0 | 1.642 | |
detox/ox | lulogut46050 | XP_001843663.1 cytochrome P450 4C1 | 0 | 1.484 | |
detox/ox | lulogut36308 | probable cytochrome P450 6a14 | 0 | 1.368 | |
met/lipd | lulogut34584 | XP_001651935.1 epoxide hydrolase 1 | 5.00E-92 | 1.363 | |
detox | lulogut45588 | JAV13724.1 glutathione s-transferase-like protein | 3.00E-77 | 1.353 | |
detox/ox | lulogutSigP-48,117 | probable cytochrome P450 6a14 | 0 | 1.173 | |
detox/ox | lulogut15028 | XP_001870174.1 cytochrome P450 6a8 | 0 | 1.145 | |
12d | detox/ox | lulogut32543 | XP_001870174.1 cytochrome P450 6a8 | 0 | 1.592 |
met/nuc | lulogut42037 | JAV11176.1 alkaline nuclease partial | 0 | 1.307 | |
met/lipd | lulogut50375 | Long chain fatty acid acyl-CoA ligase | 4.00E-52 | 1.252 | |
detox | lulogut33084 | Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies | 0 | 1.221 | |
pe | lulogutSigP-54,446 | Peptide exporter ABC superfamily | 3.00E-59 | 1.189 | |
detox/ox | lulogutSigP-8474 | probable cytochrome P450 6a14 | 0 | 1.171 | |
detox | lulogutSigP-34,911 | Cytochrome P450 CYP3/CYP5/CYP6/CYP9 subfamilies | 1.00E-59 | 1.107 | |
detox/ox | lulogut237 | XP_001649312.1 probable cytochrome P450 6d5 | 1.00E-68 | 1.093 | |
14d | met/carb | lulogut56076 | JAV12467.1 udp-glucoronosyl and udp-glucosyl transferase | 0 | 2.140 |
detox | lulogut13235 | ABV44726.1 glutathione S-transferase-like protein | 2.00E-88 | 1.692 | |
detox/ox | lulogutSigP-8474 | probable cytochrome P450 6a14 | 0 | 1.359 | |
met/lipd | lulogut34584 | XP_001651935.1 epoxide hydrolase 1 | 5.00E-92 | 1.258 | |
detox/ox | lulogut32543 | XP_001870174.1 cytochrome P450 6a8 | 0 | 1.239 | |
met/lipd | lulogutSigP-34,488 | Acyl-CoA synthetase - probable fragment - signalP detected | 7.00E-83 | 1.217 | |
met/carb | lulogutSigP-34,624 | JAV12537.1 udp-glucoronosyl and udp-glucosyl transferase | 0 | 1.181 | |
detox/ox | lulogut237 | XP_001649312.1 probable cytochrome P450 6d5 | 1.00E-68 | 1.174 |