Table 4 Top five down- regulated midgut transcripts upon Leishmania infection per time point
From: Leishmania infection induces a limited differential gene expression in the sand fly midgut
Time Point | Class | Transcript name | Putative Encoded Protein | E-value | LFC |
|---|---|---|---|---|---|
1d | nr | lulogut42801 | DNA damage-responsive repressor GIS1/RPH1 jumonji superfamily | 0 | −1.419 |
2d | st | lulogut40195 | NP_523758.3 juvenile hormone esterase isoform A | 6.00E-29 | −1.823 |
tr | lulogutSigP-32,510 | Permease of the major facilitator superfamily | 0 | −1.9194 | |
tr | lulogutSigP-46,620 | Permease of the major facilitator superfamily | 9.00E-85 | −2.538 | |
tf | lulogut44569 | Forkhead/HNF-3-related transcription factor | 3.00E-90 | −2.960 | |
tr | lulogut21743 | JAV05033.1 sodium/potassium-transporting atpase subunit beta-2-like protein | 0 | −2.991 | |
st | lulogutSigP-22,907 | Acetylcholinesterase/Butyrylcholinesterase | 4.00E-54 | −5.397 | |
s/met/lipd | lulogutSigP-23,161 | AAO22149.1 mammalian-like lipase | 0 | −5.688 | |
uk | lulogutSigP-18,032 | Unknown product | NA | −5.917 | |
4d | s/uk | lulogutSigP-14,897 | hypothetical secreted protein precursor | 1000 | −3.861 |
met/lipd | lulogut21836 | JAV11771.1 lipid storage droplets surface-binding protein 1 | 0 | −3.861 | |
s/met/nuc | lulogutSigP-26,492 | JAV11299.1 deoxyribonuclease partial | 0 | −4.105 | |
s/protin | lulogutSigP-16,416 | BPTI/Kunitz family of serine protease inhibitors | 8.00E-17 | −4.125 | |
met/carb | lulogut25316 | Hexokinase | 0 | −4.299 | |
s/ uk | lulogutSigP-16,502 | hypothetical conserved secreted protein precursor | NA | −4.926 | |
s/uk | lulogut36242 | hypothetical secreted protein precursor | 1000 | −5.523 | |
s/ | lulogutSigP-24,104 | JAV08889.1 juvenile hormone binding protein in insects | 0 | −8.423 | |
12d | detox | lulogut19743 | JAV03807.1 metallothionein-2-like protein | 2.00E-34 | −2.909 |
storage | lulogut21324 | JAV06440.1 ovotransferrin partial | 0 | −3.778 | |
s/uk | lulogutSigP-16,502 | hypothetical conserved secreted protein precursor | NA | −3.893 | |
s/protinh | lulogutSigP-16,416 | BPTI/Kunitz family of serine protease inhibitors - signalP detected | 8.00E-17 | −3.902 | |
tm | lulogutSigP-15,657 | nucleolar and coiled-body phosphoprotein 1 isoform X2 Drosophila ficusphila | 4.00E-21 | −4.086 | |
pm/protease | lulogut25198 | JAV08757.1 trypsin | 0 | −4.383 | |
s/ | lulogutSigP-24,035 | JAV08413.1 secreted mucin | 0 | −4.536 | |
met/lipd | lulogut41307 | JAV11511.1 ecdysteroid kinase | 0 | −6.148 | |
14d | met/nuc | lulogut40330 | Uridylate kinase/adenylate kinase | 4E-59 | −1.292 |