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Fig. 5 | BMC Genomics

Fig. 5

From: RNA-seq analysis of galaninergic neurons from ventrolateral preoptic nucleus identifies expression changes between sleep and wake

Fig. 5

Heat map of fold-changes between sleep deprivation and sleep at each time point in VLPO-Gal neurons and mPFC. Cell colors with red indicates up-regulation with SDep and blue indicates up-regulation with sleep. Row annotations indicate biological functions. a Genes involved in protein folding and transcription are commonly up-regulated with SDep in both VLPO-Gal and mPFC, whereas translation and cell differentiation are commonly up-regulated with sleep in both VLPO-Gal and mPFC. b Sixteen genes show opposite direction of change between VLPO-Gal and mPFC cells. Twelve genes were up-regulated with SDep in VLPO-Gal neurons but up-regulated with sleep in mPFC. Functions played by these genes include DNA repair and neuronal development. Four genes (Mnt, Cry2, Lrrc23, and Igsf11) were up-regulated with sleep in VLPO-Gal but up-regulated with SDep in mPFC

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BMC Genomics

ISSN: 1471-2164

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