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Table 1 Top 20 human genes linked to alcohol problems and epigenetics

From: SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol

Human gene PubMed Citations Worm Gene Expression
Alcohol problems Epigenetics Gene Expression
STAT3 87 363 sta-1 Up
GSTP1 19 284 gst-16 Down
gst-39 Up
gst-38 Up
gst-19 Down
EP300 1 153 cbp-1 Down
NOTCH1 7 149 glp-1 Down
SLC6A4 193 123 snf-11 Up
CREBBP 6 123 cbp-1 Down
STAT1 26 113 sta-1 Up
TLR4 202 102 tol-1 Down
SFN 2 96 ftt-2 Up
VDR 7 95 nhr-8 Up
RHOA 7 62 rho-1 Down
TLR2 42 58 tol-1 Down
FRY 19 58 sax-2 Down
ABCB1 6 58 pgp-5 Up
AGO2 2 58 alg-2 Down
alg-5 Down
HNF4A 9 56 nhr-35 Up
nhr-60 Down
STAT4 4 45 sta-1 Up
RAC1 6 42 ced-10 Down
LMNA 2 41 ifd-2 Down
ifd-1 Up
KAT5 1 40 mys-4 Down