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Table 4 DEGs encoding metabolism related proteins and transcription factors/ co-activators from T. castaneum responding to dsTcAMPKα treatment

From: Metabolic and transcriptome responses of RNAi-mediated AMPKα knockdown in Tribolium castaneum

Unigene name padj Description
(blast)
Length
(ORF bp)
Log2Ratio
Transcriptome
Log2Ratio
qRT-PCR
Lipid metabolism
 FAS1 0.038775298 fatty acid synthase 12,981 1.02 0.37
 FAS2 0.056982009 fatty acid synthase 6522 1.76 0.71
 FAS3 0.260213539 fatty acid synthase 7152 0.79 1.05
 FAS4 0.425672932 fatty acid synthase 6630 0.63 1.16
 FAS5 0.170696071 fatty acid synthase 6450 0.58 1.53
 ACC 0.186316184 acetyl-CoA carboxylase 7005 0.83 0.10
 GPAT3 0.046646995 glycerol-3-phosphate acyltransferases 1440 0.67 1.51
 Brummer 1.60E-05 triacylglycerol lipase 1635 −2.20 −0.37
Carbohydrate metabolism
 TRE1–1 0.036902117 Trehalase1–1 1662 0.89 1.46
 TRE1–3 0.450009964 Trehalase1–3 > 507 0.56 0.58
 TRE1–4 0.007152475 Trehalase1–4 1812 0.68 0.59
 TRE2 0.036902117 Trehalase2 1647 0.89 1.61
Insulin signaling pathway
 IRS1 0.018687502 insulin receptor substrate 2760 1.13 0.63
 InR2 0.004419643 insulin-like receptor 4185 1.09 0.23
 PI3K 3.37E-08 phosphatidylinositol 4,5-bisphosphate 3-kinase 3186 1.02 0.63
Transcription factor and co-activator
 SCAP 0.031742692 sterol regulatory element binding protein cleavage-activating protein 3783 0.81 1.12
 SREBP1 0.036908768 sterol regulatory element binding protein 1 3078 0.94 1.74
 ChREBP 0.000606393 carbohydrate response-element-binding protein 510 1.18 1.94