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Table 1 Significant gene expression changes in the hypothalamo-pituitary-gonadal (HPG) axis between egg production levels. Fold change and significance are presented for key HPG axis genes outside and during the preovulatory surge (RPKM> 0.2, P < 0.05). Negative fold change values represent increased expression in low egg producing hens (LEPH) and positive fold change values represent increased expression in high egg producing hens (HEPH)

From: Transcriptome analysis of the hypothalamus and pituitary of turkey hens with low and high egg production

Tissue

Gene

Function

Fold

P-Value

Outside Preovulatory Surge

Hypothalamus

PRL

prolactin signaling

−2.65

0.0245

CYP19A1

steroid hormone biosynthesis

−1.52

0.0292

CYP1A1

steroid hormone biosynthesis

1.92

0.0092

HSD11B1

steroid hormone biosynthesis

1.67

0.0448

Pituitary

CGA

HPG axis signaling

1.59

0.0217

AR

steroid hormone signaling

−1.59

0.0126

STAR

steroid hormone biosynthesis

−16.73

0.0000

During Preovulatory Surge

Tissue

Gene

Function

Fold

P-Value

Hypothalamus

GNRH1

HPG axis signaling

−2.54

0.0362

NPVF

HPG axis signaling

−1.78

8.39E-06

FSHR

HPG axis signaling

−7.03

0.0002

ESR2

steroid hormone signaling

1.35

0.0218

PRL

prolactin signaling

1.87

0.0299