Fig. 3

Characterization of tissue-specific consensus open chromatin. a Number of consensus peaks demonstrating tissue-specific accessibility in each tissue and species. b Normalized ATAC-seq signal (RPM) at regions demonstrating tissue-specific accessibility in cattle and pig tissues. Tissue-specific peaks were first grouped by corresponding tissue, then ordered by signal intensity. Peaks were scaled to 500 bp, and signal is shown 500 bp upstream and downstream. c Distribution of tissue-specific open chromatin relative to gene annotations. d Enrichment of known TF binding motifs in tissue-specific open chromatin. Motifs sorted by TF family. Sets of tissue-specific open chromatin for each species are grouped by tissue. Increasing size and color intensity indicate increasing enrichment for a given motif