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Fig. 7 | BMC Genomics

Fig. 7

From: Liver transcriptome profiling and functional analysis of intrauterine growth restriction (IUGR) piglets reveals a genetic correction and sexual-dimorphic gene expression during postnatal development

Fig. 7

Detailed functional profiling of DEGs (P < 0.05, FC > 2 or < 0.5) between the male IUGR and male NBW piglets. a Classification of the GO terms based on the functional annotation of BP enriched in male IUGR piglets on Day 1. The ordinate represents the GO item, the abscissa represents the number of enriched DEGs corresponding to each term, and the color column represents the enrichment score (defined as -Log10 P-value). b The GOCircle plot of the male IUGR piglets on Day 1. The outer circle shows a scatter plot for each term of the logFC of the assigned genes. Red circles display the up-regulation and the blue circles indicate down-regulation by default. c The GOChord plot of male IUGR piglets on Day 1 and the DEGs that were assigned to at least three process terms were selected. d The protein-protein interaction network of the DEGs in male IUGR piglets on Day 1. The red nodes indicate upregulation and the green nodes indicate downregulation in IUGR piglets. Fold changes (FC) in expression are expressed as log2 (FC) values. e The tables show the major functions of the DEGs that were selected in the male IUGR piglets on Day 1. f The GO enrichment analysis of the DEGs of BP enriched in the male IUGR piglets on Day 7. g GO enrichment analysis of the DEGs of BP enriched in the male IUGR piglets on Day 28

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