Fig. 9
From: Clustering analysis of large-scale phenotypic data in the model filamentous fungus Neurospora crassa
Model showing predicted pathway(s) for genes that co-cluster with the ERK MAPK genes in Cluster 40. The MAK-1 and MAK-2 ERK MAPK cascade genes are represented by green and red shading, respectively. S. cerevisiae interaction data for genes in Cluster 40 were obtained from www.yeastgenome.org. Physical interactions, genetic interactions, or physical and genetic interactions between the indicated genes/gene products in yeast are shown by yellow, blue, or green lines, respectively. Genes with known interactions in N. crassa are connected by black lines. Genes that interact with the MAK-1 cascade kinases are shaded in yellow, while those that interact with components of the MAK-2 pathway are indicated with blue shading. Genes with no ortholog in yeast and no known interaction in N. crassa are represented by the white rectangles