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Fig. 3 | BMC Genomics

Fig. 3

From: Functional module detection through integration of single-cell RNA sequencing data with protein–protein interaction networks

Fig. 3

(Upper Panel) Network plots of the detected modules for three choices of the FDR (10−25,10−24, and 10−18). The colour of the nodes shows their p-value from low (white) to high (purple). We indicate proteins that would not have been discovered from the gene-expression data alone as squares and give their names in bold red font. (Lower Panel) The size of detected modules (blue disks) depends on the FDR. A large fraction of proteins in these modules have significant p-values (red squares), however, for all FDR >10−26, we also identify additional proteins as for a given FDR, the blue disks are to the right of the red disks

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