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Fig. 4 | BMC Genomics

Fig. 4

From: Functional module detection through integration of single-cell RNA sequencing data with protein–protein interaction networks

Fig. 4

Detected modules for six hepatocyte clusters for FDR=10−27.We find that the detected modules vary in size, with the smallest consisting of a single protein and the largest consisting of 253 proteins (we omit the largest cluster for visualisation purposes). Colour indicates p-value of associated gene from low (white) to high (purple). We show nodes as squares if they would not have been detected without PPIN information. For the larger modules, we only give the names of these proteins that we would not have detected by a DEG analysis. See SI for an illustration which includes protein names

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