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Fig. 5 | BMC Genomics

Fig. 5

From: Molecular signature comprising 11 platelet-genes enables accurate blood-based diagnosis of NSCLC

Fig. 5

Gene panel shares a regulatory circuit. Graphical representation of the enriched transcription factor binding sites in the 1 kilobase upstream region (TSS=0) of 11 gene signature. p-value (FDR-corrected) represents the statistical power depicting a significant enrichment of the indicated motifs in the given region over shuffled control sequences. Bar graphs on the right represent normalized read-counts of the identified transcriptional factors between healthy and tumor samples. Asterisks represent p-value significance. p-value cutoff was set to 0.05. *, **, *** and **** represent the p-values of ≤0.05, ≤0.01, ≤0.001 and ≤0.0001 respectively

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