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Fig. 2 | BMC Genomics

Fig. 2

From: Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection

Fig. 2

Unique and shared differentially expressed genes (DEG) in fetal tissues. Proportional-area Venn Diagrams: A) Placenta DEG each group contrasted to control (CTRL); low viral load with viable (LVL-VIA) or with meconium staining (LVL-MEC), high viral load with viable (HVL-VIA) or with meconium staining (HVL-MEC). B) Fetal thymus DEG each group contrasted to CTRL; LVL-VIA, LVL-MEC, HVL-VIA, and HVL-MEC. C) Placenta on the left and thymus on the right with DEG in V + F (LVL-VIA, LVL-MEC, HVL-VIA, and HVL-MEC) contrasted to V - F [UNINF, placenta only with VIA (PLCO-VIA), and PLCO-MEC]. D) Placenta on the left and thymus on the right with DEG in MEC + F (PLCO-MEC, LVL-MEC, and HVL-MEC) contrasted to MEC - F (UNINF, PLCO-VIA, LVL-VIA, and HVL-VIA). Bubble sizes are based on relative numbers of DEG for a given contrast calculated using the Euler method. Red is LVL-VIA, yellow is LVL-MEC, blue is HVL-VIA, green is HVL-MEC, orange is V + F, and grey is MEC + F+

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BMC Genomics

ISSN: 1471-2164

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