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Table 2 Number and directionality of DEG by contrast

From: Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection

Contrast (group 1 – group 2)a Placenta Fetal thymus
Group 1 Group 2 Down-Regulated DEG Up-Regulated DEG Total DEG Down-Regulated DEG Up-Regulated DEG Total DEG
UNINF CTRL 0 0 0 0 0 0
PLCO-VIA CTRL 0 0 0 0 0 0
PLCO-MEC CTRL 0 0 0 0 0 0
LVL-VIA CTRL 0 11 11 1 8 9
LVL-MEC CTRL 25 33 58 2 9 11
HVL-VIA CTRL 36 46 82 84 30 114
HVL-MEC CTRL 27 62 89 30 34 64
V + F (LVL-VIA + LVL-MEC + HVL-VIA + HVL-MEC) V (UNINF + PLCO-VIA + PLCO-MEC) 77 47 124 97 35 132
MEC + F (PLCO-MEC + LVL-MEC + HVL-MEC) MEC (UNINF + PLCO-VIA + LVL-VIA + HVL-VIA) 0 7 7 1 2 3
  1. aEach group of fetuses was contrasted with the control (mock infected) group. Additionally, virus positive fetuses aka V + F (LVL-VIA + LVL-MEC + HVL-VIA + HVL-MEC) were contrasted with virus negative fetuses aka V - F (UNINF + PLCO-VIA + PLCO-MEC) as well as meconium-stained fetuses aka MEC + F (PLCO-MEC + LVL-MEC + HVL-MEC) versus viable fetuses aka MEC - F (UNINF + PLCO-VIA + LVL-VIA + HVL-VIA)