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Fig. 4 | BMC Genomics

Fig. 4

From: Identification, expression, and artificial selection of silkworm epigenetic modification enzymes

Fig. 4

Single variant site selective sweeping analysis. a Detailed artificial selection analysis and predicted TF binding on selected variants of BmSuv4–20. b Detailed artificial selection analysis and predicted TF binding on selected variants of BmDNMT2. Top: Diagram for gene structure and artificial selection analysis of BmSuv4–20 (a) and BmDNMT2 (b) in 1-kb windows. Orange, deep blue, and green plots in each window represent the average value of πlocal, FST wild_local, and RODdomesticated, respectively. The x-axis represents the physical location of the genomic region of BmSuv4–20 (a) and BmDNMT2 (b). The selected regions are situated between the two dotted lines. Middle: Details of selection signatures of each variant in selected regions. 3 and 1 variants were detected with significant selection in the 5′-flanking region of BmSuv4–20 (A) and BmDNMT2 (B), respectively. Gray shaded areas indicate sites with strong selection signatures (πlocal < 0.00095, FST wild_local > 0.75095, and RODdomesticated > 0.939). Bottom: The difference of predicted TF binding on selected variants between reference and altered genotypes. POS: genomic position of the variant; REF: reference genotype of the variant. ALT: altered genotype of the variant. “/” indicates no predicted TF-binding sites

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