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Table 2 Catalytic residues of Argonautes of the Ago, Piwi and Wago groups in Acari species, Caenorhabditis elegans, Drosophila melanogaster and Tribolium castaneum

From: A genome-wide screening for RNAi pathway proteins in Acari

  1. Argonautes shown are from Caenorhabditis elegans (Ce), Drosophila melanogaster (Dm), Tribolium Castaneum (Tc), Ixodes Scapularis (Is), Metaseiulus occidentalis (Mo), Tropilaelaps mercedesae (Tm), Varroa destructor (Vd), Varroa jacobsoni (Vj), Tetranychus urticae (Tu), Dermatophagoides farinae (Df), Psoroptes ovis (Po), Euroglyphus maynei (Em), Dermatophagoides pteronyssinus (Dp), and Sarcoptes scabiei (Ss). The amino acid sequences of the PIWI domains were aligned with MAFFT [42]. Substitutions for the Aspartate-Aspartate-Histidine (Asp-Asp-His) motif such as Aspartate or Histidine to either Serine (S), Arginine (R), Alanine (A), Asparagine (N), Glycine (G) or Tyrosine (Y), are colored in pink. Substitutions of the Histidine to Aspartate (D) or Lysine (K) are colored in light blue. (−) indicate the absence of amino acid residues from the sequence