Table 4 Gene oncology (GO) clustering analysis of differentially expressed genes (DEGs; |fold change| > 1.5 at a false discovery rate < 0.05)

 antigen processing and presentation of peptide antigen via MHC class I

GO:0002474

4

 positive regulation of T cell mediated cytotoxicity

GO:0001916

4

 regulation of catabolic process

GO:0009894

2

 antigen processing and presentation

GO:0019882

5

 protein ubiquitination involved in ubiquitin-dependent protein catabolic process

GO:0071947

2

 protein modification by small protein conjugation or removal

GO:0070647

5

 cellular protein modification process

GO:0006464

10

 protein modification process

GO:0036211

10

 macromolecule modification

GO:0043412

10

 MHC class I protein complex

GO:0042612

4

 membrane

GO:0016020

41

 integral component of membrane

GO:0016021

25

 mitochondrion

GO:0005739

4

 cytoplasmic part

GO:0044444

16

 endomembrane system

GO:0012505

8

 membrane part

GO:0044425

34

 endosome

GO:0005768

3

 intrinsic component of membrane

GO:0031224

27

 extracellular matrix

GO:0031012

3

 peptide antigen binding

GO:0042605

4

 catalytic activity

GO:0003824

29

 identical protein binding

GO:0042802

2

 transferase activity

GO:0016740

11

 antigen binding

GO:0003823

4

 calcium ion binding

GO:0005509

5

 adenyl ribonucleotide binding

GO:0032559

3

 ATP binding

GO:0005524

3

 ion binding

GO:0043167

31

 adenyl nucleotide binding

GO:0030554

3

 oxidoreductase activity

GO:0016491

3

 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

GO:0016705

2

 voltage-gated calcium channel activity

GO:0005245

2