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Fig. 2 | BMC Genomics

Fig. 2

From: Cell-specific characterization of the placental methylome

Fig. 2

Differential methylation at DNA methylation -regulating genes. a On a per-gene basis, the number of promoter CpGs that are differentially methylated by at least one cell type, out of the total number of promoter CpGs per gene. The yā€‰=ā€‰x line is shown (blue), where genes with 100% of promoter CpGs are differentially methylated. The green line is a smoothed average. b Distribution of the percentage of promoter CpGs per gene that are differentially methylated. The dotted line represents an array-wide average. c DNA methylation at CpGs associated with DNMT1 for term placental samples (top). CpGs in CpG islands, imprinted regions, PMDs, and enhancers are indicated (middle). Associated UCSC transcripts and their genomic elements (promoter, 5ā€² UTR, exons, introns, 3ā€™UTR) are displayed (bottom)

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