Table 2 Number of preeclampsia-associated CpGs from Wilson et al. 2018 that are cell-specific DMCs for term samples. Enrichment for preeclampsia-associated CpGs was statistically significant for each term cell-specific set of CpGs at a Bonferroni-adjusted p < 0.01
From: Cell-specific characterization of the placental methylome
n cell-specific DMCs | n DMCs that are preeclampsia-associated | Proportion out of 599 preeclampsia CpGs that are also cell-specific DMCs | Odds ratio | |
|---|---|---|---|---|
Trophoblast | 135,553 | 147 (0.11%) | 27.2% | 1.66 |
Stromal | 80,153 | 105 (0.13%) | 19.4% | 1.98 |
Endothelial | 75,525 | 109 (0.14%) | 20.2% | 2.22 |
Hofbauer Cells | 130,733 | 131 (0.10%) | 24.3% | 1.49 |