Fig. 6
From: jouvence, a new human snoRNA involved in the control of cell proliferation
Hundreds of genes are deregulated in jouvence depleted HCT116 cells. a Transcriptomic analysis (RNA-Seq) performed on total-RNA (enriched for poly-A) from the knockdown of jouvence by siRNA on HCT116 cells compared to the control non-transfected cells, reveals that 6263 genes are deregulated, in which 3098 are upregulated, while 3165 are downregulated (see Suppl. Table S4 and Suppl. Table S5 for the complete list of genes). b Statistic of pathway enrichment of the deregulated genes according to the KEGG analysis (see Suppl. Table S6 for the full list of the KEGG analysis). In brief, the metabolic pathways are the main deregulated pathways in term of number of genes, while the ribosome and spliceosome are the two main deregulated pathways in term of strength (Rich factor)