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Fig. 2 | BMC Genomics

Fig. 2

From: Genomic analysis of worldwide sheep breeds reveals PDGFD as a major target of fat-tail selection in sheep

Fig. 2

Analysis of sequence variations of PDGFD gene. a The distribution of the absolute difference of allele frequency ΔAF of sequence variation within the 24 identified genes with selection signatures between 13 fat-tailed sheep individuals and 16 thin-tailed sheep individuals from different regions. The sequence variations were downloaded from NextGene project. The red dashed line indicates the threshold value (ΔAF > 0.6). The bottom panel shows the distribution of the absolute difference of allele frequency ΔAF of sequence variation within PDGFD gene. The red dashed line indicates the threshold value (ΔAF > 0.6) and red dots represents SNPs with ΔAF > 0.9. b Haplotype compassion between thin-tailed and fat-tailed sheep obtained based on all the variations within the highly differentiated 6.8-kb genomic interval (Chr15:3,854,063-3,860,894 bp). Each column is a polymorphic genomic location (122 in total), each row is a phased haplotype (16 thin-tailed sheep and 13 fat-tailed sheep individuals), and alternative alleles are labelled in blue. c Derived allele frequency of the 13 top candidate SNPs in additional fat-tailed sheep (Chinese Tan sheep) and thin-tailed sheep (Chinese Tibetan sheep) obtained by Sequenom MassARRAY

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