Comparative analysis of the transcriptomes of EDL, psoas, and soleus muscles from mice

BMC Genomics

Table 1 Genes with the highest correlation to principal components 1 and 2. The top 10 genes with the highest loading to PC1 and PC2 are shown. The Pearson correlation coefficients of FPKM values of selected genes to principal components are denoted by R²

Principal component	Gene symbol	Gene name	R²
PC1	Myh7	Myosin, heavy polypeptide 7, cardiac muscle, beta	0.92
	Myl2	Myosin, light polypeptide 2, regulatory, cardiac, slow	0.91
	Tnni1	Troponin I, skeletal, slow 1	0.91
	Tnnt1	Troponin T1, skeletal, slow	0.97
	Tpm3	Tropomyosin 3, gamma	0.96
	Myh6	Myosin, heavy polypeptide 6, cardiac muscle, alpha	0.89
	Atp2a2	Atpase, Ca++ transporting, cardiac muscle, slow twitch 2	0.97
	Myl3	Myosin, light polypeptide 3	0.96
	Tnnc1	Troponin C, cardiac/slow skeletal	0.94
	Strit1	Small transmembrane regulator of ion transport 1	0.87
PC2	Col11a1	Collagen, type XI, alpha 1	0.89
	Kera	Keratocan	0.92
	Wif1	Wnt inhibitory factor 1	0.91
	Tnmd	Tenomodulin	0.95
	Cilp2	Cartilage intermediate layer protein 2	0.86
	Tnc	Tenascin C	0.92
	Ecrg4	ECRG4 augurin precursor	0.87
	Lars2	Leucyl-trna synthetase, mitochondrial	−0.49
	Col1a1	Collagen, type I, alpha 1	0.80
	Col11a2	Collagen, type XI, alpha 2	0.81

ISSN: 1471-2164