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Fig. 4 | BMC Genomics

Fig. 4

From: Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands

Fig. 4

Statistical filter process. The stepwise process for ranking and categorizing the CpG methylation patterns of genomic CGIs permitted the ranking of CGI changes between edited and control animal CGIs. Significantly changed CGIs followed a path (yellow bars) toward Case 1 based on significant p-value changes with Bonferroni correction and filtered beyond biological epigenetic noise

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