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Table 2 Statistical and epigenetic noise filtering of experimental and control CGI methylome comparisons

From: Detection of CRISPR-mediated genome modifications through altered methylation patterns of CpG islands

  1. The table summarizes the results of evaluating Animals HDR1, HDR2, NHEJ1, and Control 2 against Animal Control 1 using the methodology for identifying significant changes in methylation patterns for CGIs defined in Fig. 4. *Note: The α level of 0.05 was adjusted using the Bonferroni method for each comparison; the adjusted α = 0.05/Total CGIs. Each animal was compared against Control 1 Animal. The blue highlight indicates the Case containing the CRISPR-edited CGI for the respective animal
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BMC Genomics

ISSN: 1471-2164

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