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Table 1 Odds Ratio for the CFA18 SNP Significantly Associated with Addison’s Disease

From: Genetic characterization of Addison’s disease in Bearded Collies

CFA18 SNP (BICF2P1230367–28,207,384; CanFam3.1 reference allele G)#
Genotype Controls
(N = 85)
AD cases
(N = 55)
OR (95% CI)* p-value
A A 7 9 2.2 (0.76–6.25) 0.17613
G A 19 30 4.2 (2.00–8.70) 0.00013
G G 59 16 0.2 (0.09–0.38) 4.72 × 10−6
A A 7 9   
vs 4.7 (1.53–14.70) 0.00742
G G 59 16
G A 19 30
vs 5.8 (2.62–12.92) 0.00001
G G 59 16
  1. Odds ratio (OR) for the CFA18 single nucleotide polymorphism (SNP) associated with Addison’s disease (AD) in 140 Bearded Collies (55 AD cases, 85 healthy controls). Bolded values were statistically significant at p < 0.05.
  2. *CI Confidence interval, #SNP location is based on the CanFam3.1 reference genome