Table 2 Odds Ratio for the Top Suggestive SNPs on CFAs 11, 16, and 29
From: Genetic characterization of Addison’s disease in Bearded Collies
Genotype | Controls (N = 85) | AD cases (N = 55) | OR (95% CI)* | p-value |
|---|---|---|---|---|
CFA11 SNP (BICF2G630307993–71,446,591; CanFam3.1 reference allele A)# | ||||
G G | 1 | 11 | 21.0 (2.63–167.99) | 0.00015 |
G A | 29 | 23 | 1.4 (0.69–2.79) | 0.37576 |
A A | 55 | 21 | 0.3 (0.17–0.68) | 0.00303 |
G G | 1 | 11 | ||
vs | 28.8 (3.50–237.15) | 0.00004 | ||
A A | 55 | 21 | ||
G A | 29 | 23 | ||
vs | 2.1 (0.99–4.37) | 0.06010 | ||
A A | 55 | 21 | ||
CFA16 SNP (BICF2G630109748–27,126,780; CanFam3.1 reference allele C) | ||||
G G | 40 | 43 | 4.0 (1.87–8.70) | 0.00038 |
C G | 35 | 12 | 0.4 (0.18–0.86) | 0.02728 |
C C | 10 | 0 | NA§ | 0.01403 |
G G | 40 | 43 | ||
vs | NA | 0.00151 | ||
C C | 10 | 0 | ||
C G | 35 | 12 | ||
vs | NA | 0.09974 | ||
C C | 10 | 0 | ||
CFA29 SNP (BICF2P977298–30,615,809; CanFam3.1 reference allele A) | ||||
C C | 16 | 27 | 4.2 (1.95–8.88) | 0.00019 |
C A | 47 | 20 | 0.5 (0.23–0.93) | 0.03760 |
A A | 22 | 8 | 0.5 (0.20–1.19) | 0.14087 |
C C | 16 | 27 | ||
vs | 4.6 (1.68–12.85) | 0.00397 | ||
A A | 22 | 8 | ||
C A | 47 | 20 | ||
vs | 1.2 (0.45–3.07) | 0.81259 | ||
A A | 22 | 8 | ||