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Table 1 Subject characteristics

From: Exploring protocol bias in airway microbiome studies: one versus two PCR steps and 16S rRNA gene region V3 V4 versus V4

  Controls COPD Asthma
Subjects 9 10 4
Age, mean ± SD years 63.0 ± 6.7 68.2 ± 5.2 63.6 ± 3.1
Men 6 (66.7%) 8 (80.0%) 2 (50.0%)
Current-smokers 2 (22.2%) 1 (10.0%) 0
Former-smokers 5 (55.6%) 9 (90.0%) 3 (75.0%)
Never-smokers 2 (22.2%) 0 1 (25.0%)
Smoker pack years, mean ± SD years 11.8 ± 6.1 25.2 ± 8.1 12.1 ± 6.2
FEV1 (% predicted), mean ± SD 97.0 ± 13.7 72.6 ± 23.2 101.6 ± 9.3
Inhaled corticosteroids 0 2 (20.0%) 3 (75.0%)
LABA 0 3 (30.0%) 1 (25.0%)
LAMA 0 4 (40.0%) 0
  1. COPD Chronic obstructive pulmonary disease; FEV1 Forced expiratory volume in 1 s; LABA Long-acting beta-agonist; LAMA Long-acting muscarinic antagonist. 1 smoker pack year = 20 cigarettes (one pack) smoked daily for 1 year. Age, smoker pack years and FEV1 (% predicted) are presented as the mean ± standard deviation.SD: standard deviation.