Skip to main content

Table 2 GWAS Replication Testing

From: Whole genome sequencing identified a 16 kilobase deletion on ECA13 associated with distichiasis in Friesian horses

Name Original sample p-value Replication sample p-value Combined p-value
ECA13:g.340918C > T 2.26 × 10−8 1.61 × 10−5 5.71 × 10− 14
ECA13:g.343850A > C 2.26 × 10− 8 1.61 × 10− 5 5.71 × 10− 14
ECA13:g.330462G > A 2.73 × 10− 7 2.34 × 10− 5 8.58 × 10− 13
ECA13:g.425443C > T 4.16 × 10− 7 1.45 × 10− 4 1.64 × 10− 11
ECA13:g.230097C > T 2.27 × 10− 7 2.30 × 10− 4 2.31 × 10− 11
ECA13:g.134040A > G 8.15 × 10− 8 3.07 × 10− 4 2.31 × 10− 11
ECA13:g.142416C > T 2.27 × 10− 7 3.07 × 10− 4 2.73 × 10− 11
ECA13:g.153435C > T 2.27 × 10− 7 3.07 × 10− 4 2.73 × 10− 11
ECA13:g.195278 T > C 2.27 × 10− 7 3.07 × 10− 4 2.73 × 10− 11
ECA13:g.198581G > C 2.27 × 10− 7 3.07 × 10− 4 2.73 × 10− 11
ECA13:g.200759 T > C 2.27 × 10− 7 3.07 × 10− 4 2.73 × 10− 11
ECA13:g.201534G > A 2.27 × 10− 7 3.07 × 10− 4 2.73 × 10− 11
ECA13:g.206996G > A 2.27 × 10− 7 4.06 × 10− 4 3.75 × 10− 11
ECA13:g.121325G > A 2.73 × 10− 7 1.07 × 10− 3 1.12 × 10− 11
ECA13:g.122064G > A 2.73 × 10− 7 1.07 × 10− 3 1.12 × 10− 11
ECA13:g.122243C > T 2.73 × 10− 7 1.07 × 10− 3 1.12 × 10− 11
ECA13:g.316346C > T 2.73 × 10− 7 1.07 × 10− 3 1.12 × 10− 11
ECA13:g.13611A > G 7.73 × 10− 7 1.10 × 10− 3 3.94 × 10− 10
ECA13:g.42897A > G 2.73 × 10− 7 1.10 × 10− 3 1.45 × 10− 10
ECA13:g.32112G > T 8.48 × 10− 7 1.39 × 10− 3 1.36 × 10− 9
ECA13:g.384663 T > C 5.94 × 10− 6 2.00 × 10− 3 5.77 × 10− 9
ECA13:g.15928A > G 8.15 × 10− 8 0.0288 2.04 × 10− 9
ECA5:g.39962594G > A 4.57 × 10− 6 0.404 4.65 × 10− 9
ECA5:g.39863319A > Ga 4.57 × 10− 6 0.478 1.28 × 10− 5
ECA12:g.3271275C > A 9.10 × 10− 6 0.716 6.75 × 10− 4
ECA12:g.3270900 T > C 1.57 × 10− 5 1 4.65 × 10− 4
ECA13:g.186975G > Ab 1 1 1
ECA13:g.189306C > Tb 1 1 1
ECA13:g.190216 T > Cb 1 1 1
  1. a This SNP was assessed through a PCR-RFLP analysis
  2. bAs these SNPs fall within the 16 kb deletion, they only yielded results in one case (see Fig. 5)