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Table 3 Orthologs and their species of origin identified by amino acid sequence similarity using EGGNOG

From: Bioinformatic analysis and functional predictions of selected regeneration-associated transcripts expressed by zebrafish microglia

Gene IDa

Ortholog ID

Function

Evalueb

Species

P1

ENSLACG00000022667

Protein tyrosine kinase

1.23e-200

Latimeria chalumnae

MOS

v-mos Moloney murine sarcoma viral oncogene homolog

1.86e-27

Xenopus (Silurana) tropicalis

BLK

B lymphoid tyrosine kinase

1.03e-11

Takifugu rubripes

Mst1r

Macrophage stimulating 1 receptor

2.07e-7

Mus musculus

CSF1R

Colony stimulating factor 1 receptor

5.21e-4

Xenopus (Silurana) tropicalis

P2

JGI99580

Unknown

6.68e-259

Branchiostoma floridae

P3

ENSGMOG00000016627

Unknown

1.5e-127

Gadus morhua

ENSLACG00000005016

Immunoglobulin V-set domain

3.08e-10

Latimeria chalumnae

PDGFRB

Growth factor receptor

6.45e-7

Xenopus (Silurana) tropicalis

NPHS1

Nephrosis 1, congenital, Finnish type (nephrin)

1.97e-5

Xenopus (Silurana) tropicalis

LOC414035

Lachesin

9.06e-5

Apis mellifera

P4

BASP1

Unknown

1.63e-5

Oryzias latipes

P5

ENSXMAG00000002763

Unknown

7.04e-17

Xiphophorus maculatus

JGI72098

SH3

2.17e-4

Phanerochaete chrysosporium

PTPRA

Protein tyrosine phosphatase, receptor type, A

8.33e-4

Xenopus (Silurana) tropicalis

P6

ARC2

CD46 molecule, complement regulatory protein

8.30e-4

Xenopus (Silurana) tropicalis

P7

ENSXMAG00000014998

Unknown

9.61e-44

Xiphophorus maculatus

P8

ENSLACG00000014033

CD84 molecule

1.05e-112

Latimeria chalumnae

ENSXMAG00000015872

Lymphocyte antigen 9

2.03e-77

Xiphophorus maculatus

ENSGALG00000007355

Immunoglobulin V-set domain

1.22e-09

Latimeria chalumnae

CEACAM6

Carcinoembryonic antigen-related cell adhesion molecule

1.41e-09

Takifugu rubripes

HMCN1

Hemicentin

3.28e-06

Xenopus (Silurana) tropicalis

P9

ENSXMAG00000013611

Urotensin II

2.24e-70

Xiphophorus maculatus

P10

ENSG00000143185

Chemokine (C motif) ligand

3.22e-14

Gorilla gorilla

ENSXMAG00000019244

Small cytokines (intecrine/chemokine), interleukin-8 like

3.86e-6

Xiphophorus maculatus

P11

GANAB

Glucosidase, alpha

1.38e-307

Xenopus (Silurana) tropicalis

P12

 

No orthologs found

  
  1. Orthologs found for the studied genes using the protein sequence similarity approach EggNOG 4.5.1 [55]
  2. aGene ID: P1 to P12 correspond to the symbol used for each predicted protein subjected to bioinformatics analysis
  3. bThe Expect value (E-value) or random background noise is the number of hits one can “expect” to see by chance when searching a database of a particular size (https://blast.ncbi.nlm.nih.gov). The lower the E-value, or the closer it is to zero, the more “significant” the match is