Fig. 5
From: Meta-Apo improves accuracy of 16S-amplicon-based prediction of microbiome function
Functional beta diversity of the 2655 WGS samples and the 5350 amplicon samples from Dataset 3. a Functional patterns derived from the amplicon and WGS approaches are separate with significant differences on PC1 and PC2 distributions. b Meta-Apo aligns the predicted functional profiles of amplicon samples to those of the WGS samples using 15 sample pairs for training, making the PC1 and PC2 of calibrated functional profiles of amplicon samples are closer to WGS samples than the original, non-calibrated amplicon samples. Principle coordinates were calculated by PCoA using the Bray-Curtis distances. The p-values were calculated by two-tail Wilcox tests, and *** denotes p < 0.01