Domain structures of Ankyrin-repeat containing proteins in Ehrlichia sp. HF. Ehrlichia sp. HF encodes 5 Ank-repeat containing proteins, including E. chaffeensis Ank200 homolog (EHF_0607). Ank-repeat domains were determined by NCBI Conserved Domains Database (CDD, https://www.ncbi.nlm.nih.gov/Structure/cdd) [140, 141], and eukaryotic phosphorylation sites were determined by Scansite 4.0 (https://scansite4.mit.edu/) . In addition to 14 Ank repeats, Ank200 (EHF_0607) contains two tyrosine kinase phosphorylation sites (red bars), two SH3 domains (blue), and one Ser/Thr kinase site (green). Domain abbreviations: Ank, Ankyrin repeat; DUF5401, family of unknown function initially found in Chromadorea like Caenorhabditis elegans; NtpI, Archaeal/vacuolar-type H+-ATPase subunit I/STV1.