Fig. 4

Concerted age- and state-dependent antennal gene regulation spanning gene families. Two regulation motifs (a and b) are demonstrated by the transcript abundance in 5 to 10 days post-emergence (dpe) non-blood fed (nbf; green; left) and age-matched blood fed (bf; brown; middle) Aedes aegypti female antennae. Comparisons between nbf (black) and age-matched bf (blue) antennal transcript abundance are described by fold change (right). Permanent gene identifiers along with the common gene names are to the left. Ball and stick diagrams represent the general trend in abundance demonstrated by this gene family (a motif 1, top right; b motif 2, top right). Asterisks between two age groups denote stringent significant difference (> 2-fold change; FDR P < 0.05). Asterisks to the far right of each table indicate significant differences between 5 and 10 dpe.  a These genes demonstrate a motif 1 pattern of transcript regulation, while b are those that demonstrate motif 2