Multi-trait GWAS using imputed high-density genotypes from whole-genome sequencing identifies genes associated with body traits in Nile tilapia

Table 2 Genetic parameters and comparison of association results between single- and multi-trait GWAS for Nile tilapia

Trait	\( {\boldsymbol{\sigma}}_{\boldsymbol{a}}^{\mathbf{2}} \)	h²	SE	Single-trait			Multi-trait
Trait	\( {\boldsymbol{\sigma}}_{\boldsymbol{a}}^{\mathbf{2}} \)	h²	SE	Significant SNP	-log (p-value)^a	Mean χ²	Significant SNP^a	-log (p-value)^a	Mean χ²	N GWAS equivalent
ADG	0.406	0.422	0.046	1	7.524	1.674	1359	14.581	1.815	1582
BWH	27,334.76	0.423	0.045	1	7.632	1.693	1209	14.392	1.781	1474
WW	10,937.59	0.386	0.046	1	7.454	1.718	1347	14.600	1.907	1654
HW	1658.12	0.450	0.045	0	5.706	1.727	1595	14.389	1.898	1617
HON	10,516.63	0.435	0.045	1	7.452	1.514	1138	13.005	1.694	1766
BLH	2.855	0.414	0.045	0	5.631	1.749	827	17.147	2.081	1890
FW	2951.46	0.343	0.045	1	7.592	1.541	833	17.750	1.649	1605
FY	0.0001	0.210	0.039	1	8.503	1.273	1920	11.622	1.335	1569

^aFor the most significant SNP; ADG average daily gain (g), BWH body weight at harvest (g), WW waste weight (g), HW head weight (g), HON gutted head-on weight (g), BLH body length at harvest (cm), FW fillet weight (g), FY fillet yield (%)

ISSN: 1471-2164