Fig. 2From: De novo ZIC2 frameshift variant associated with frontonasal dysplasia in a Limousin calfComputed tomography of the skull of the affected calf (a, c) and a control animal (b, d). The control animal was a Holstein calf. a In the rostrocaudal view the absence of the maxilla, nasal and incisive bones and the non-fused os frontale were striking features. Also the rudimentary orbita and the cleft palate were evident. c Left lateral view displays the strongly curved malformed mandible. The four pairs of incisive teeth were positioned near to the coronoid process. The molars and premolars were rudimentary curvedBack to article page