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Fig. 7 | BMC Genomics

Fig. 7

From: Regulatory roles of differentially expressed MicroRNAs in metabolic processes in negative Lens-induced myopia Guinea pigs

Fig. 7

miR-novel-chrscaffold-128-37,706 targeted PPAR α. (a) the sequence of 3′-UTR where PPAR α mRNA bound to miR-novel-chrscaffold-128-37,706; (b) dual-luciferase reporter gene assay, which showed that miR-novel-chrscaffold-128-37,706 mimics could inhibit the luciferase activity of miR-novel-chrscaffold-128-37,706/PPAR α-WT plasmid. However, it had no effect on the luciferase activity of miR-novel-chrscaffold-128-37,706/PPAR α-MT. *P < 0.05; WT, wild type; MT, mutant type

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