Fig. 1
From: Identification of functional regulatory elements in the human genome using pooled CRISPR screens
p53 knockout increases cell proliferation. a Distribution of p53 enrichment scores from pooled CRISPR knockout screens in 350 cancer cell lines. b p53 enrichment scores in a selected subset of cancer cell lines containing wildtype p53. c Western blot analysis of Cas9 expression in 769P cells. d Comparison of log2 fold changes (relative to pDNA) for all sgRNAs in CRISPR library between replicates. e Visualization of enrichment/depletion for sgRNAs targeting a selected subset of genes (red) compared to all sgRNAs in CRISPR library (black)