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Fig. 2 | BMC Genomics

Fig. 2

From: Choice of library size normalization and statistical methods for differential gene expression analysis in balanced two-group comparisons for RNA-seq studies

Fig. 2

False positive rates estimated via intra-group analysis of 379 OC samples with different read depths. Illustrated are the fractions of FPs estimated from the RLE, TMM, UQ and UQ-pgQ2 normalization with the exact test, QL F-test or Wald test for sample sizes of 5, 10, 15, 20, 25, 30, 35 and 40. The plots are based on a read depth from 19 to 157 million (a-c), from 12.8 to 104 million (d-f), and from 9.6 to 78.6 million (g-i)

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BMC Genomics

ISSN: 1471-2164

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