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Fig. 5 | BMC Genomics

Fig. 5

From: Genome-wide discovery, and computational and transcriptional characterization of an AIG gene family in the freshwater snail Biomphalaria glabrata, a vector for Schistosoma mansoni

Fig. 5

Heatmap of organ specific expression of B. glabrata AIG genes. RNA-Seq reads from 12 organs of B. glabrata BB02 [36] were analyzed. Blocks in the heat map were colored in reference to Z scores transformed from transcripts per million (TPM). Z scores were calculated as (TPM – mean across organ)/standard deviation across organs. The Z score is a cross-organ normalization of TPM for each individual gene, and for a given gene, Z scores among organs are comparable. To compare gene expression within one specific organ, TPM was used. VectorBase transcript IDs were used to match with a specific AIG gene on each row. Those IDs with an asterisk are B. glabrata GIMAPs. IDs in green were target sequences of microarray probes in the study on gene expression of B. glabrata BS-90 strain (schistosome-resistant) injected with pathogens [24]. IDs in orange were homologs of AIG genes (cut-off values: > 70% identity; > 90% coverages) for a related snail, B. pfeifferi, from RNA-Seq data [25]. IDs in mustard color were AIG genes that appeared in both studies above

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BMC Genomics

ISSN: 1471-2164

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