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Fig. 1 | BMC Genomics

Fig. 1

From: RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio

Fig. 1

Heatmap, volcano and MA plots. a The heatmap of up- and down-regulated genes in orange and blue, respectively. b The volcano plot was constructed by plotting the negative log of the log10 FDR value on the y-axis. This results in data points with low log10 FDR values (highly significant) appearing toward the top of the plot. The x-axis is the logFC between the two conditions (wild and mutant zebrafish). c MA plot visualizes the differences between measurements taken in wild and mutant zebrafish DEGs, by transforming the data into M (log ratio) and A (mean average) scales logCPM (counts per million) and logFC, then plotting these values. The orange color indicates the significant genes, and the black color indicates non-significant genes

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