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Fig. 2 | BMC Genomics

Fig. 2

From: In silico identification and assessment of insecticide target sites in the genome of the small hive beetle, Aethina tumida

Fig. 2

Alternative splicing of nicotinic acetylcholine receptor subunits (nAChRs) in the small hive beetle, Aethina tumida. a Variation in the intron acceptor splice site in Atumα3 that adds 12 nucleotides to the 5′ end of exon 11. Amino acids shown in bold appear under the first base of the codon. Exon sequences are shown within borders. The shaded sequence represents the alternative intron splice site sequence that is added in XM_020016025.1. Dashes represent intron 10 of Atumα3 (not to scale). b Predicted transcript from Atumα6. Alternatively-spliced exons 3a/3b and 8a/8b/8c are shaded black and gray, respectively. The conserved exon 8b is not present in the genomic sequence and appears as a box with dotted border. Exons are shown as boxes and sizes are approximately proportional to nucleotide length. Introns shown as lines connecting the boxes are not to scale. c Schematic diagram of missing genomic region of Atumα7 compared to Tcasα7. Atumα7 is lacking equivalents of exons 6 and 7 from Tcasα7. Letters and numbers at the top of the diagram represent the approximate locations of ligand binding loops and transmembrane domains, respectively. Exons are shown as boxes and sizes are approximately proportional to nucleotide length. Introns shown as lines connecting the boxes are not to scale

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