Improved recovery of cell-cycle gene expression in Saccharomyces cerevisiae from regulatory interactions in multiple omics data

Table 2 Observed and expected numbers of FFLs in GRNs defined using different data sets

Data Set	# observed FFLs	μ expected^a	σ² expected^a	Z-score^b
ChIP	3777	811	28.47	104.15
Deletion	13,162	2427	49.26	217.90
PWM1	75,514	52,915	230.03	98.24
PWM2	1700	398	19.94	65.26
PBM	67,895	47,371	217.64	94.30

^aThe mean (μ) and standard deviation (σ²) of FFLs expected in a GRN was determined using the cube of the mean connectivity of the GRN (see Methods)
^bThe z-score reflects the difference between the observed and expected number of FFLs divided by the standard deviation of the expected number of FFLs (see Methods)

ISSN: 1471-2164