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Table 3 Enriched pathways by upregulated proteins in Kashmiri and Jersey cattle

From: Comparative milk proteome analysis of Kashmiri and Jersey cattle identifies differential expression of key proteins involved in immune system regulation and milk quality

PathwayProteinsp-valueFDRProteinsGenes
Kashmiri cattle
 Beta3 adrenergic receptor signaling pathway (P04379)20.072650.1719P11017, P62871GNB2, GNB1
 Beta2 adrenergic receptor signaling pathway (P04378)20.095760.8552P11017, P62871GNB2, GNB1
 Metabotropic glutamate receptor group III pathway (P00039)20.01240.0723P11017, P62871GNB2, GNB1
 Beta1 adrenergic receptor signaling pathway (P04377)20.005990.0543P11017, P62871GNB2, GNB1
 5HT4 type receptor mediated signaling pathway (P04376)20.073870.1987P11017, P62871GNB2, GNB1
 5HT2 type receptor mediated signaling pathway (P04374)20.01410.0792P11017, P62871GNB2, GNB1
 5HT1 type receptor mediated signaling pathway (P04373)20.096710.1897
0.049
P11017, P62871GNB2, GNB1
 Integrin signalling pathway (P00034)20.08230.353P63258, E1BBG2ACTG1, MICALL1
 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway (P00026)20.06580.298P11017, P62871GNB2, GNB1
 Wnt signaling pathway (P00057)30.03880.197P63258, P11017, P62871GNB2, GNB1, ACTG1
 Thyrotropin-releasing hormone receptor signaling pathway (P04394)20.0820.759P11017, P62871GNB2, GNB1
 FGF signaling pathway (P00021)20.04170.2P63103, P68250YWHAZ,YWHAB
 EGF receptor signaling pathway (P00018)400.041P63103, Q95115, P68250, Q9TTC5YWHAZ, STAT5A, YWHAB, BTC
 PI3 kinase pathway (P00048)30.0020.0685P63103, P11017, P62871GNB2, GNB1, YWHAZ
 Opioid prodynorphin pathway (P05916)20.004060.0602P11017, P62871GNB2, GNB1
 Histamine H1 receptor mediated signaling pathway (P04385)20.006470.0502P11017, P62871GNB2, GNB1
 Enkephalin release (P05913)20.003870.0701P11017, P62871GNB2, GNB1
 Angiotensin II-stimulated signaling through G proteins and beta-arrestin (P05911)20.004880.0497P11017, P62871GNB2, GNB1
 CCKR signaling map (P06959)20.08160.36P62871, P68250GNB1,YWHAB
 Metabotropic glutamate receptor group II pathway (P00040)20.006470.0527P11017, P62871GNB2, GNB1
Jersey Cattle
 Integrin signalling pathway (P00034)20.08790.796P62998, Q2TBH2RAC1, RRAS
 EGF receptor signaling pathway (P00018)30.006630.36P62998, Q2TBH2, Q95115RAC1, RRAS, STAT5A
 PDGF signaling pathway (P00047)20.05670.66Q148J4, Q95115RAB2A, STAT5A
 Blood coagulation (P00011)30.0004280.0698P34955, P41361, P28800SERPINA1, SERPINC1, SERPINF2
 CCKR signaling map (P06959)20.08720.836P17697, P62998CLU, RAC1
 T cell activation (P00053)20.03180.648P01888, P62998B2M, RAC1
 TGF-beta signaling pathway (P00052)20.02980.694Q2TBH2, P21214RRAS, TGFB2
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