Fig. 6

Capturing chromatin decondensation in Lamin KO cells. a Boxplots representing change in Hi-C read counts in the LAD domains after Lamin knock out in mESC cells. P-value was calculated using two-tailed Mann-Whitney U test. b-c Examples representing change in Hi-C read counts and contact matrices in WT and Lamin KO cells. The bottom panel of matrices represent the Lamin KO to WT fold-change in interaction frequencies