Fig. 2
From: Sirt2-associated transcriptome modifications in cisplatin-induced neuronal injury
Differential transcriptomes in Sirt2-expressing and Sirt2-deficient cells. a Venn diagram showing calculated differentially expressed genes by Deseq2 and EdgeR. b PCA analysis for Sirt2-expressing and Sirt2-deficient samples. c Volcano plot of differentially expressed genes. Red represents an increase in expression; blue represents a decrease; and grey indicates no significant difference. d Western blot for Sirt2 in Sirt2/Ctrl, Sirt2-expressing, and Sirt2-deficient cells. Vinculin used as a loading control. e Heatmap of differentially expressed genes with fold change > 2, Red represents an increase in expression; blue represents a decrease