Sirt2-associated transcriptome modifications in cisplatin-induced neuronal injury

BMC Genomics

Table 2 Fold change by qPCR of cisplatin-induced transcriptome in association with Sirt2

Symbol	Sirt2-expressing (treated vs untreated)		Sirt2-deficient (treated vs untreated)
Symbol	RNAseq (FC)	qPCR (FC)	RNAseq (FC)	qPCR (FC)
Klhdc8a	10.09	2.59*	5.33	2.47*
Bmp7	5.22	2.57*	3.15	2.30*
p21	3.43	5.23*	5.15	5.45*
Mycn	0.88	0.72	0.32	0.47*
Igfbp5	0.47	0.38*	0.68	0.45*
Abcc9	0.44	0.38*	0.45	0.29*
Slc2a13	0.32	0.48*	0.25	0.37*
Tceal3	0.22	0.63	2.02	1.94*
Kcnj8	0.153	0.36*	7.63	1.69

FC Fold change. Untreated Sirt2-expressing and Sirt2-deficient were used as a reference, respectively. All genes were normalized to Gapdh. FC > 2 or < 0.5 considered significant. *P < 0.05

ISSN: 1471-2164