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Fig. 5 | BMC Genomics

Fig. 5

From: Deep in the Bowel: Highly Interpretable Neural Encoder-Decoder Networks Predict Gut Metabolites from Gut Microbiome

Fig. 5

This figure shows a three layer graph relating microbe abundances to the top 10 best predicted metabolite abundances, built using the edge overlap across all 5 model instances. Yellow nodes are significantly enriched in healthy guts, while blue nodes are significantly enriched in IBD guts. The middle layer contains latent variables that weigh the bacteria abundances so that they maximally predict the metabolite abundances. Most of these latent variables, learned in a fully unsupervised way, are themselves significantly associated with IBD

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BMC Genomics

ISSN: 1471-2164

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