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Table 2 Effects of non-synonymous and loss of function mutations on colony size, as inferred by Elastic Net regression. Effect sizes are relative to the initial colony size. The functional units were defined using Ecocyc [24]

From: Dissection of the mutation accumulation process during bacterial range expansions

• Name • Gene description • Pos. Coef. • Neg. Coef. • Function unit
• croE • RNA polymerase assembly factor • 0.867 • DNA or RNA process
• livM • Transporter • 0.705 • Transporter
• ybiO • Transporter • 0.243 • Transporter
• ycfQ • Transcriptional repressor • 0.679 • Regulator
• fdoG • Formate dehydrogenase • 0.627 • Metabolic process
• ybdH • Swarming motility • 0.066 • Motility
• yheT • Predicted hydrolase • −3.766 • Metabolic process
• frlD • Phosphorylation • −0.695 • Metabolic process
• metL • Amino acid biosynthesis • −0.686 • Metabolic process
• pdxJ • Metabolic process • −0.596 • Metabolic process
• fixC • Flavoprotein • −0.593 • Metabolic process
• glnE • Glutamine synthesis • −0.533 • Metabolic process
• yphB • Conserved protein • −0.508 • Metabolic process
• yfeS • Conserved protein • −0.381 • Metabolic process
• ybhJ • Metabolic process • −0.181 • Metabolic process
• elbB • Lycopene biosynthesis • −0.177 • Metabolic process
• panC • Biosynthetic process • −0.104 • Metabolic process
• msyB • Heat sensitivity • −0.081 • Metabolic process
• gtrB • Prophage • −0.076 • Metabolic process
• hpc • Nitrate metabolism • −0.044 • Metabolic process
• dmlA • D-malate dehydrogenase • −0.032 • Metabolic process
• yfiL • Lipoprotein • −1.484 • Membrane
• wcaL • Colanic acid synthesis • −0.507 • Membrane
• lnt • Lipoprotein • −0.228 • Membrane
• yfjD • Inner membrane protein • −0.124 • Membrane
• yciM • Lipopolysaccharide assembly • −0.072 • Membrane
• ddpA • Peptide ABC transporter • −0.904 • Transporter
• fecC • Transporter • −0.751 • Transporter
• yqcE • Transporter • −0.282 • Transporter
• pheP • Phenylalanine transporter • −0.103 • Transporter
• alsA • Transporter • −0.081 • Transporter
• ccmB • Transporter • −0.073 • Transporter
• uidB • Glucuronide transporter • −0.045 • Transporter
• paaX • Regulator • −0.784 • Regulator
• rssB • Regulator of RpoS • −0.649 • Regulator
• preA • Swarming motility • −0.497 • Motility
• yeaJ • Motility • −0.011 • Motility
• recG • DNA repair • −0.245 • DNA or RNA process
• der • Ribosomal stability factor • −0.238 • DNA or RNA process
• leuP • tRNA • −0.188 • DNA or RNA process