Table 3 Top 10 gene ontology biological processes from EnrichR regulated in the CON group (A) and PRO group (B) based on the total number of genes that was significantly regulated in the CON group (n = 440) and PRO group (n = 892) group (F-test q-value< 0.05)
A | Name of biological process | Genes (n) | P-value | Q-value |
|---|---|---|---|---|
1 | extracellular matrix organization | 25 | 0.000 | 0.000 |
2 | sarcomere organization | 7 | 0.000 | 0.002 |
3 | muscle contraction | 19 | 0.000 | 0.000 |
4 | positive regulation of sprouting angiogenesis | 7 | 0.000 | 0.001 |
5 | positive regulation of B cell differentiation | 3 | 0.001 | 0.041 |
6 | regulation of angiogenesis | 16 | 0.000 | 0.001 |
7 | mitochondrial ATP synthesis coupled proton transport | 3 | 0.012 | 0.180 |
8 | regulation of release of sequestered calcium ion into cytosol | 8 | 0.000 | 0.003 |
9 | actomyosin structure organization | 11 | 0.000 | 0.000 |
10 | myofibril assembly | 8 | 0.000 | 0.002 |
B | Name of biological process | Genes (n) | P-value | Q-value |
1 | extracellular matrix organization | 55 | 0.000 | 0.000 |
2 | regulation of smooth muscle cell migration | 8 | 0.001 | 0.000 |
3 | mitochondrial ATP synthesis coupled proton transport | 5 | 0.002 | 0.075 |
4 | collagen fibril organization | 11 | 0.000 | 0.000 |
5 | regulation of angiogenesis | 25 | 0.000 | 0.000 |
6 | positive regulation of cell migration | 27 | 0.000 | 0.001 |
7 | positive regulation of smooth muscle cell migration | 4 | 0.001 | 0.049 |
8 | regulated exocytosis | 19 | 0.000 | 0.005 |
9 | basement membrane organization | 4 | 0.000 | 0.026 |
10 | cellular protein modification process | 76 | 0.000 | 0.001 |